Rubidium in PDB 7awp: Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101

The structure of Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101, PDB code: 7awp was solved by J.C.Canul-Tec, P.Legrand, N.Reyes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.00 / 3.91
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	124.375, 124.375, 91.438, 90, 90, 120
R / Rfree (%)	24.6 / 29.1

The structure of Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101 also contains other interesting chemical elements:

Barium

(Ba)

2 atoms

The binding sites of Rubidium atom in the Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101 (pdb code 7awp). This binding sites where shown within 5.0 Angstroms radius around Rubidium atom.
In total only one binding site of Rubidium was determined in the Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101, PDB code: 7awp:

Rubidium binding site 1 out of 1 in the Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101


Mono view


Stereo pair view

A full contact list of Rubidium with other atoms in the Rb binding site number 1 of Structure of the Thermostabilized EAAT1 Cryst-II Mutant in Complex with Rubidium and Barium Ions and the Allosteric Inhibitor UCPH101 within 5.0Å range: probe atom residue distance (Å) B Occ A:Rb604 b:146.9 occ:1.00 O A:SER343 2.7 101.0 1.0 OD1 A:ASP456 3.3 124.9 1.0 NH2 A:ARG459 3.8 129.1 1.0 C A:SER343 3.9 100.0 1.0 OG1 A:THR460 3.9 105.9 1.0 CA A:SER344 4.1 86.4 1.0 CG A:ASP456 4.3 130.5 1.0 N A:SER344 4.4 91.0 1.0 CB A:SER344 4.6 89.3 1.0 NE A:ARG459 4.6 125.7 1.0 CZ A:ARG459 4.6 135.6 1.0 OD2 A:ASP456 4.6 138.4 1.0 OG A:SER343 4.7 115.6 1.0 OG A:SER344 4.9 93.9 1.0

J.Canul-Tec, J.Dhenin, R.Assal, P.Legrand, R.Martial, J.Chamoot-Rooke, N.Reyes. Ion-Coupling Mechanism of Excitatory Amino Acid Transporters To Be Published.